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Index > Protein center > Pdcd1(Gene name) > Mouse
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  • Pdcd1 (Gene name),
  • Programmed cell death protein 1 (Protein name ),  PDCD1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Pdcd1(Pd1);
    Protein name:
    Programmed cell death protein 1(Protein PD-1;mPD-1);
    Alternative:

    CD:
    CD279;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Inhibitory cell surface receptor involved in the regulation of T cell function during immunity and tolerance. Upon ligand binding, inhibits T cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    288
    Sequence:
    50:
    MWVRQVPWSF | TWAVLQLSWQ | SGWLLEVPNG | PWRSLTFYPA | WLTVSEGANA | 
    100:
    TFTCSLSNWS | EDLMLNWNRL | SPSNQTEKQA | AFCNGLSQPV | QDARFQIIQL | 
    150:
    PNRHDFHMNI | LDTRRNDSGI | YLCGAISLHP | KAKIEESPGA | ELVVTERILE | 
    200:
    TSTRYPSPSP | KPEGRFQGMV | IGIMSALVGI | PVLLLLAWAL | AVFCSTSMSE | 
    250:
    ARGAGSKDDT | LKEEPSAAPV | PSVAYEELDF | QGREKTPELP | TACVHTEYAT | 
    288:
    IVFTEGLGAS | AMGRRGSADG | LQGPRPPRHE | DGHCSWPL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Protein PD-1
    Cat.:
    E0515h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Protein PD-1
    Cat.:
    E0515m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Protein PD-1
    Cat.:
    U0515h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Protein PD-1
    Cat.:
    U0515m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Protein PD-1
    Cat.:
    P0515Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Protein PD-1
    Cat.:
    P0515Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Protein PD-1
    Monoclonal Antibody for Mouse Protein PD-1
    Protein for Mouse Protein PD-1
    Protein for Mouse Protein PD-1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death."
      Ishida Y. , Agata Y. , Shibahara K. , Honjo T.
      EMBO J.11:3887-3895(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structural and functional analysis of the costimulatory receptor programmed death-1."
      Zhang X. , Schwartz J.C. , Guo X. , Bhatia S. , Cao E. , Lorenz M. , Cammer M. , Chen L. , Zhang Z.-Y. , Edidin M.A. , Nathenson S.G. , Almo S.C.
      Immunity20:337-347(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 34-150;SUBUNIT;DISULFIDE BOND
    3. 3.
      "The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors."
      Lin D.Y. , Tanaka Y. , Iwasaki M. , Gittis A.G. , Su H.P. , Mikami B. , Okazaki T. , Honjo T. , Minato N. , Garboczi D.N.
      Proc. Natl. Acad. Sci. U.S.A.105:3011-3016(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF 25-157 IN COMPLEX WITH CD274;DISULFIDE BOND
    4. 4.
      "Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2."
      Lazar-Molnar E. , Yan Q. , Cao E. , Ramagopal U. , Nathenson S.G. , Almo S.C.
      Proc. Natl. Acad. Sci. U.S.A.105:10483-10488(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 34-150 IN COMPLEX WITH PDCD1LG2;DISULFIDE BOND
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